Leishmaniasis is a pestilent affliction that importunately needs better therapeutics necessitated by absence of effective vaccine, emergence as HIV co-infection and the dread of debilitating chemotherapy.The Leishmania parasites incapacitate host macrophages by preventing the formation of phagolysosomes, impeding antigen presentation to T cells, le
Tomato yellow leaf curl virus (TYLCV) and its related begomoviruses cause fast-spreading diseases in tomato worldwide.How this virus induces diseases remains largely unclear.Here we report a High Voltage Capacitor noncoding RNA-mediated model to elucidate the molecular mechanisms of TYLCV-tomato interaction and disease development.The circular ssDN
Background: Aluminium reduces severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) survival in experimental settings.It is unknown whether adding an aluminium gauze to a mask reduces the SARS-CoV-2 RNA load in the mask and whether SARS-CoV-2 is detectable in the breath that permeates through such a mask in clinical settings.Methods: Patient
Design and objectives A cross-sectional study to evaluate the impact of COVID-19 on the psychosocial sphere in both the general population and healthcare workers (HCWs).Methods The study HR Wire Harness was conducted in Catalonia (Spain) during the first wave of the COVID-19 pandemic when strict lockdown was in force.The study population included a
IntroductionThe sexual quality of life is a neglected concern in women living with HIV (WHIV) or with HCV (WHCV), which can further be affected by their experience with stigma, social instability, fear of transmission and reduced access to treatment.The objective of this study was to identify sociodemographic, psychosocial, and behavioural factors